How Primordial Germ Cells Destroy Somatic Signals

Lynn Cooley

doi:10.1016/j.devcel.2017.07.005

How Primordial Germ Cells Destroy Somatic Signals

Dev Cell. 2017 Jul 24;42(2):107-108. doi: 10.1016/j.devcel.2017.07.005.

Author

Lynn Cooley¹

Affiliation

¹ Departments of Genetics, Cell Biology and Molecular, Cellular & Developmental Biology, Yale University, New Haven, CT 06520, USA. Electronic address: lynn.cooley@yale.edu.

PMID: 28742996
DOI: 10.1016/j.devcel.2017.07.005

Abstract

The Germ Cell-Less (GCL) protein is a key regulator of primordial germ cell (PGC) formation in Drosophila embryos. Reporting in this issue of Developmental Cell, Pae et al. (2017) show that GCL blocks somatic cell fate by specifically destroying the Torso Receptor Tyrosine Kinase.

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MeSH terms

Animals
Drosophila
Drosophila Proteins*
Germ Cells*
Receptor Protein-Tyrosine Kinases

Substances

Drosophila Proteins
Receptor Protein-Tyrosine Kinases