Clinical evaluation of combined azacitidine and entinostat on the induction of fetal hemoglobin in patients with acute myeloid leukemias and myelodysplastic syndromes

Leuk Lymphoma. 2018 Mar;59(3):755-757. doi: 10.1080/10428194.2017.1354373. Epub 2017 Jul 25.

Authors

Katharine R Press¹, Natalie Uy², Jeffrey Keefer³, Steven D Gore², Hetty E Carraway⁴, Sarah Sakoian³, Thomas Prebet²

Affiliations

¹ a Department of Pediatrics , Columbia University Medical Center , NY , USA.
² b Deptartment of Internal Medicine, Section of Hematology , Yale University School of Medicine , New Haven , CT , USA.
³ c Johns Hopkins University School of Medicine , Baltimore , MD , USA.
⁴ d Taussig Cancer Institute, Hematologic Oncology and Blood Disorders , Cleveland Clinic , Cleveland , OH , USA.

PMID: 28738707
DOI: 10.1080/10428194.2017.1354373

No abstract available

Publication types

Evaluation Study

MeSH terms

Aged
Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
Azacitidine / administration & dosage
Benzamides / administration & dosage
Clinical Trials, Phase I as Topic
Female
Fetal Hemoglobin / analysis*
Follow-Up Studies
Humans
Leukemia, Myeloid, Acute / blood*
Leukemia, Myeloid, Acute / drug therapy
Leukemia, Myeloid, Acute / pathology
Male
Myelodysplastic Syndromes / blood*
Myelodysplastic Syndromes / drug therapy
Myelodysplastic Syndromes / pathology
Prognosis
Pyridines / administration & dosage

Substances

Benzamides
Pyridines
entinostat
Fetal Hemoglobin
Azacitidine