The safety of available and emerging options for emergency contraception

Expert Opin Drug Saf. 2017 Oct;16(10):1163-1171. doi: 10.1080/14740338.2017.1354985. Epub 2017 Jul 27.

Abstract

Emergency contraception (EC) is a way to significantly reduce the chance of becoming pregnant after an episode of unprotected intercourse. Considerable data support the safety of all available and emerging options for EC. Areas covered: This review presents a comprehensive summary of the literature regarding the safety of EC as well as directions for further study. PubMed was searched for all relevant studies published prior to June 2017. Expertopinion: All available methods of EC (i.e., ulipristal acetate pills, levonorgestrel pills, and the copper-IUD), carry only mild side effects and serious adverse events are essentially unknown. The copper IUD has the highest efficacy of EC methods. Given the excellent safety profiles of mifepristone and the levonorgestrel IUD, research is ongoing related to use of these products for EC.

Keywords: Copper IUD; emergency contraception safety; levonorgestrel emergency contraceptive pill; ulipristal acetate.

Publication types

  • Review

MeSH terms

  • Animals
  • Contraception, Postcoital / adverse effects
  • Contraception, Postcoital / methods*
  • Contraceptives, Postcoital / administration & dosage*
  • Contraceptives, Postcoital / adverse effects
  • Female
  • Humans
  • Intrauterine Devices, Copper / adverse effects
  • Levonorgestrel / administration & dosage
  • Levonorgestrel / adverse effects
  • Norpregnadienes / administration & dosage
  • Norpregnadienes / adverse effects
  • Pregnancy

Substances

  • Contraceptives, Postcoital
  • Norpregnadienes
  • Levonorgestrel
  • ulipristal acetate