Ribosomes Need Straight A's to Sleep

Samuel B Sondalle; Susan J Baserga

doi:10.1016/j.cell.2017.04.019

Ribosomes Need Straight A's to Sleep

Cell. 2017 May 4;169(4):565-567. doi: 10.1016/j.cell.2017.04.019.

Authors

Samuel B Sondalle¹, Susan J Baserga²

Affiliations

¹ Department of Genetics, Yale University School of Medicine, New Haven, CT 06520, USA.
² Department of Genetics, Yale University School of Medicine, New Haven, CT 06520, USA; Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, CT 06520, USA; Department Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06520, USA. Electronic address: susan.baserga@yale.edu.

Abstract

Like falling asleep and waking up, many biological processes in mammals cycle in a diurnal fashion. Now, Sinturel et al. demonstrate that diurnal size changes in the liver require eating during a mouse's normal awake time and that these size changes are controlled by a nuclear mechanism that modulates ribosome production.

Publication types

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MeSH terms

Animals
Mice
Ribosomes
Sleep*
Wakefulness*

Abstract

Publication types

MeSH terms

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