Repeal and Replace: Adipocyte Regeneration in Wound Repair

Cell Stem Cell. 2017 Apr 6;20(4):424-426. doi: 10.1016/j.stem.2017.03.015.

Abstract

Adipocyte precursor cells generate lipid-filled mature adipocytes in multiple tissues during a high-fat diet and in skin during hair follicle growth. In Science, Plikus et al. report that myofibroblasts can generate lipid-filled adipocytes in large skin wounds that regenerate hair follicles, suggesting a new source of adipogenic progenitor cells.

Publication types

  • Comment

MeSH terms

  • Adipocytes*
  • Adipogenesis
  • Hair Follicle
  • Humans
  • Regeneration*
  • Wound Healing