Abstract
Dual diagnosis with substance use disorders (SUDs) consistently contributes to the premature mortality and increased disability observed in schizophrenia. Large genome-wide association studies are providing the information needed to investigate the genetic architecture of psychiatric disorders. Here, we discuss recent genetic investigations of dual diagnosis (i.e., schizophrenia plus a SUD) and how these findings can inform public health messages.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, Non-U.S. Gov't
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Research Support, N.I.H., Extramural
MeSH terms
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Diagnosis, Dual (Psychiatry)
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Genome-Wide Association Study
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Humans
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Schizophrenia / complications
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Schizophrenia / diagnosis
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Schizophrenia / etiology
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Schizophrenia / genetics*
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Substance-Related Disorders / complications
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Substance-Related Disorders / diagnosis
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Substance-Related Disorders / etiology
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Substance-Related Disorders / genetics*