A Case of Asymptomatic Inclusion Body Myositis

J Clin Neuromuscul Dis. 2017 Mar;18(3):132-134. doi: 10.1097/CND.0000000000000142.

Abstract

Objectives: To present a case of asymptomatic inclusion body myositis.

Methods: The authors report a case of a 67-year-old man who presented with idiopathic hyperCKemia. Physical examination including a complete neurological evaluation was unremarkable. Systemic causes of hyperCKemia, including medication side effects, metabolic and endocrine disorders, and connective tissue disorders, were ruled out with various indicated tests.

Results: Two and a half years after initial consultation, the patient reported left knee pain. Magnetic resonance imaging of the left knee showed edema in the mid and distal aspect of the vastus medialis and vastus lateralis muscles. A biopsy of the left quadriceps muscles was diagnostic of inclusion body myositis. He remained asymptomatic for the ensuing 2.5 years.

Conclusions: Asymptomatic hyperCKemia should be investigated and followed closely for definitive diagnosis and possible treatable causes.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Creatine Kinase / blood*
  • Humans
  • Knee Joint / diagnostic imaging*
  • Magnetic Resonance Imaging
  • Male
  • Myositis, Inclusion Body / blood
  • Myositis, Inclusion Body / complications
  • Myositis, Inclusion Body / diagnosis*
  • Myositis, Inclusion Body / diagnostic imaging
  • Pain / blood
  • Pain / diagnostic imaging
  • Pain / etiology*

Substances

  • Creatine Kinase