Thrombocytopenia

Eun-Ju Lee; Alfred Ian Lee

doi:10.1016/j.pop.2016.07.008

Thrombocytopenia

Prim Care. 2016 Dec;43(4):543-557. doi: 10.1016/j.pop.2016.07.008.

Authors

Eun-Ju Lee¹, Alfred Ian Lee²

Affiliations

¹ Division of Hematology, Weill Cornell Medical College, New York, NY, USA.
² Section of Hematology, Yale Cancer Center, Yale University School of Medicine, 333 Cedar Street, Box 208021, New Haven, CT 06520, USA. Electronic address: alfred.lee@yale.edu.

PMID: 27866576
DOI: 10.1016/j.pop.2016.07.008

Abstract

Thrombocytopenia is a commonly encountered hematologic problem in inpatient and ambulatory medicine. The many underlying mechanisms of thrombocytopenia include pseudothrombocytopenia, splenic sequestration, and marrow underproduction and destruction. This article presents the known causes of thrombocytopenia, a framework for evaluation, and brief descriptions of management in a case-based format.

Keywords: Atypical hemolytic uremic syndrome; Heparin-induced thrombocytopenia; Immune thrombocytopenia; Thrombocytopenia; Thrombotic thrombocytopenia purpura.

Publication types

Review

MeSH terms

Disease Management
Humans
Primary Health Care*
Thrombocytopenia / diagnosis*
Thrombocytopenia / therapy*