Modelling gas exchange during platelet storage without agitation

Vox Sang. 2016 Nov;111(4):445-448. doi: 10.1111/vox.12452. Epub 2016 Oct 19.

Abstract

The aim of this study was to create a model of oxygen distribution within platelet storage bags to evaluate implications of reduced agitation approaches. Based on our model, platelet concentration and surface area most affect internal partial pressure of oxygen, while temperature modifications have least effect, indicating primary potential approaches for optimization of platelet storage with reduced or absent agitation.

Keywords: platelet concentrates; platelet function; quality control.

MeSH terms

  • Blood Platelets / physiology
  • Blood Preservation / instrumentation
  • Blood Preservation / methods*
  • Carbon Dioxide / blood
  • Humans
  • Oxygen / blood
  • Permeability

Substances

  • Carbon Dioxide
  • Oxygen