A Case of a Giant Borderline Phyllodes Tumor Early in Pregnancy Treated with Mastectomy and Immediate Breast Reconstruction

Breast J. 2016 Nov;22(6):683-687. doi: 10.1111/tbj.12663. Epub 2016 Aug 26.

Abstract

Breast tumors in pregnancy are often times diagnosed at advanced stages secondary to difficulty distinguishing between pathologic from normal physiologic changes. Often benign, phyllodes tumors are rare fibroepithelial stromal tumors of the breast, most commonly diagnosed in the 4th and 5th decades of life. However, these tumors may be characterized by malignancy with metastases in 10% of cases. In this paper, we report a novel case of a young woman presenting at 8 weeks gestation with a large borderline phyllodes tumor. An exceedingly rare condition, with only nine previously reported cases, phyllodes tumors in pregnancy frequently display more aggressive characteristics with larger median tumor size, more malignant potential, and more rapid growth rate. Here, we describe our experience safely and effectively treating this rare condition in a young gravid women with mastectomy and immediate breast reconstruction in the second trimester.

Keywords: breast reconstruction; immediate reconstruction; mastectomy; phyllodes tumor; pregnancy.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Breast Neoplasms / diagnostic imaging
  • Breast Neoplasms / pathology
  • Breast Neoplasms / surgery*
  • Female
  • Humans
  • Hypertrophy / pathology
  • Mammaplasty / methods*
  • Mastectomy
  • Phyllodes Tumor / diagnostic imaging
  • Phyllodes Tumor / pathology
  • Phyllodes Tumor / surgery*
  • Pregnancy
  • Pregnancy Complications, Neoplastic / diagnostic imaging
  • Pregnancy Complications, Neoplastic / pathology
  • Pregnancy Complications, Neoplastic / surgery*
  • Pregnancy Trimester, Second
  • Ultrasonography, Mammary