Asymptomatic Plasmodium Infections in Children in Low Malaria Transmission Setting, Southwestern Uganda(1)

Emerg Infect Dis. 2016 Aug;22(8):1494-8. doi: 10.3201/eid2208.160619.

Abstract

A survey of asymptomatic children in Uganda showed Plasmodium malariae and P. falciparum parasites in 45% and 55% of microscopy-positive samples, respectively. Although 36% of microscopy-positive samples were negative by rapid diagnostic test, 75% showed P. malariae or P. ovale parasites by PCR, indicating that routine diagnostic testing misses many non-P. falciparum malarial infections.

Keywords: Africa; PCR; Plasmodium; Uganda; asymptomatic infections; children; malaria; microscopy; mosquito nets; mosquitoes; parasite; parasitic diseases; protozoan infections.

MeSH terms

  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Insecticide-Treated Bednets
  • Malaria / epidemiology*
  • Malaria / parasitology*
  • Malaria / prevention & control
  • Male
  • Parasitemia / blood
  • Prevalence
  • Uganda / epidemiology