Seizure clusters: A common, understudied and undertreated phenomenon in refractory epilepsy

Arpitha Komaragiri; Kamil Detyniecki; Lawrence J Hirsch

doi:10.1016/j.yebeh.2016.02.030

Seizure clusters: A common, understudied and undertreated phenomenon in refractory epilepsy

Epilepsy Behav. 2016 Jun:59:83-6. doi: 10.1016/j.yebeh.2016.02.030. Epub 2016 Apr 23.

Authors

Arpitha Komaragiri¹, Kamil Detyniecki², Lawrence J Hirsch²

Affiliations

¹ Comprehensive Epilepsy Center, Yale University, New Haven, CT 06520, USA. Electronic address: arpitha.komaragiri@yale.edu.
² Comprehensive Epilepsy Center, Yale University, New Haven, CT 06520, USA.

PMID: 27116535
DOI: 10.1016/j.yebeh.2016.02.030

Abstract

Epilepsy is widely prevalent globally and has emerged as a well-studied neurological condition in the recent past. Seizure clusters, a type of seizures, and several aspects pertaining to the etiopathogenesis and management of clusters are yet to be elucidated. This review is an attempt to recapitulate the current understanding of seizure clusters based on the research that has been performed on seizure clusters. This article will provide a comprehensive review of various aspects of clusters, and discusses definitions, prevalence, risk factors, impact on quality of life, approved treatment modalities, and recent advances in management.

Keywords: Acute repetitive seizures; Epilepsy; Seizure clusters; Seizures.

Publication types

Review

MeSH terms

Drug Resistant Epilepsy / diagnosis*
Drug Resistant Epilepsy / etiology
Drug Resistant Epilepsy / therapy*
Humans
Prevalence
Quality of Life
Risk Factors
Seizures / diagnosis*
Seizures / etiology
Seizures / therapy*
Syndrome
Treatment Outcome