Melanotic neuroectodermal tumor of infancy

J Clin Neurosci. 2016 Sep:31:205-7. doi: 10.1016/j.jocn.2016.02.023. Epub 2016 Apr 16.

Abstract

Melanotic neuroectodermal tumor of infancy (MNTI) is a rare pigmented craniofacial tumor of newborns and infants. We report the imaging findings of a 3-month old male patient with a maxillary MNTI. Detailed discussion on imaging features on various magnetic resonance sequences and CT scan are included. Characteristic radiographic appearance is also described. MNTI, of neural crest origin, display a biphasic population of melanin containing cells and neuroblastic cells, within a moderately vascularized fibrous stroma. The child underwent complete surgical excision with no evidence of recurrence at one year follow up. MNTI is an unusual tumor occurring in early childhood with a predilection for the maxilla. Clinical findings, CT scan and MRI may allow a preoperative diagnosis.

Keywords: CT scan; Diagnostic imaging; Infants; Magnetic resonance; Maxillary tumor; Melanotic neuroectodermal tumor.

Publication types

  • Case Reports

MeSH terms

  • Diagnosis, Differential
  • Humans
  • Infant
  • Magnetic Resonance Imaging
  • Male
  • Maxillary Neoplasms / diagnostic imaging*
  • Maxillary Neoplasms / pathology
  • Neuroectodermal Tumor, Melanotic / diagnostic imaging*
  • Neuroectodermal Tumor, Melanotic / pathology
  • Tomography, X-Ray Computed