The rs1049353 polymorphism in the CNR1 gene interacts with childhood abuse to predict posttraumatic threat symptoms

J Clin Psychiatry. 2015 Dec;76(12):e1622-3. doi: 10.4088/JCP.15l10084.

Authors

Natalie Mota^{1

2

3}, Jennifer A Sumner, Sarah R Lowe, Alexander Neumeister, Monica Uddin, Allison E Aiello, Derek E Wildman, Sandro Galea, Karestan C Koenen, Robert H Pietrzak

Affiliations

¹ US Department of Veterans Affairs National Center for Posttraumatic Stress Disorder, Clinical Neurosciences Division, VA Connecticut Healthcare System, West Haven.
² Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut.
³ Current affiliation: Department of Clinical Health Psychology, University of Manitoba, Winnipeg, Manitoba, Canada.

No abstract available

Publication types

Letter
Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Adult
Aged
Child
Child Abuse / psychology*
Fear / psychology*
Female
Gene-Environment Interaction*
Genotype
Humans
Male
Michigan
Middle Aged
Polymorphism, Genetic
Receptor, Cannabinoid, CB1 / genetics*
Severity of Illness Index
Stress Disorders, Post-Traumatic / etiology*
Stress Disorders, Post-Traumatic / genetics
Stress Disorders, Post-Traumatic / physiopathology

Substances

CNR1 protein, human
Receptor, Cannabinoid, CB1

Grants and funding