Morphologic Updates in Prostate Pathology

Adebowale J Adeniran; Peter A Humphrey

doi:10.1016/j.path.2015.08.002

Morphologic Updates in Prostate Pathology

Surg Pathol Clin. 2015 Dec;8(4):539-60. doi: 10.1016/j.path.2015.08.002.

Authors

Adebowale J Adeniran¹, Peter A Humphrey²

Affiliations

¹ Department of Pathology, Yale University School of Medicine, 310 Cedar Street, LH 108, New Haven, CT 06520, USA. Electronic address: adebowale.adeniran@yale.edu.
² Department of Pathology, Yale University School of Medicine, 310 Cedar Street, LH 108, New Haven, CT 06520, USA.

PMID: 26612214
DOI: 10.1016/j.path.2015.08.002

Abstract

In the past several years, modifications have been made to the original Gleason system with resultant therapeutic and prognostic implications. Several morphologic variants of prostatic adenocarcinoma have also been described. Prostate pathology has also evolved over the years with the discovery and utility of new immunohistochemical stains. The topics discussed in this update include the Gleason grading system, prognostic grade grouping, variants of prostatic adenocarcinoma, and the application of immunohistochemistry to prostate pathology.

Keywords: Active surveillance; Gleason system; Immunohistochemistry; Prostatic adenocarcinoma.

Publication types

Review

MeSH terms

Adenocarcinoma / pathology*
Humans
Long-Term Care / methods
Male
Neoplasm Grading
Population Surveillance / methods
Prognosis
Prostatic Neoplasms / pathology*
Watchful Waiting / methods