Stem Cells Show Parental Control

Peggy Myung; Valentina Greco

doi:10.1016/j.cell.2015.06.030

Stem Cells Show Parental Control

Cell. 2015 Jul 30;162(3):476-7. doi: 10.1016/j.cell.2015.06.030.

Authors

Peggy Myung¹, Valentina Greco²

Affiliations

¹ Department of Dermatology, Yale School of Medicine, New Haven, CT 06510, USA. Electronic address: peggy.myung@yale.edu.
² Department of Dermatology, Yale School of Medicine, New Haven, CT 06510, USA; Department of Genetics, Yale Stem Cell Center, Yale Cancer Center, Yale School of Medicine, New Haven, CT 06510, USA. Electronic address: valentina.greco@yale.edu.

PMID: 26232219
DOI: 10.1016/j.cell.2015.06.030

Abstract

Stem cells interact with their niche to maintain an undifferentiated state. The study by Pardo-Saganta et al. shows that airway basal stem cells maintain secretory daughter cells in airway epithelia through forward regulation, suggesting that stem cells may serve as a niche for their progeny.

Publication types

Comment

MeSH terms

Animals
Female
Male
Stem Cell Niche / physiology*
Stem Cells / cytology*

Grants and funding

K08 AR066790/AR/NIAMS NIH HHS/United States