Sedation in critically ill patients

Mark Oldham; Margaret A Pisani

doi:10.1016/j.ccc.2015.03.010

Sedation in critically ill patients

Crit Care Clin. 2015 Jul;31(3):563-87. doi: 10.1016/j.ccc.2015.03.010.

Authors

Mark Oldham¹, Margaret A Pisani²

Affiliations

¹ Department of Psychiatry, Yale-New Haven Hospital, 15 York Street, New Haven, CT 06510, USA.
² Section of Pulmonary, Critical Care & Sleep Medicine, Yale University School of Medicine, PO Box 208057, TAC S425C, New Haven, CT 06520-8057, USA. Electronic address: margaret.pisani@yale.edu.

PMID: 26118921
DOI: 10.1016/j.ccc.2015.03.010

Abstract

Sedation in the intensive care unit (ICU) is a topic that has been frequently researched, and debate still exists as to what are the best sedative agents for critically ill patients. There is increasing interest in sleep and circadian rhythm disturbances in the ICU and how they may impact on outcomes. In addition to patient-related and ICU environmental factors that likely impact sleep and circadian rhythm in the ICU, sedative and analgesic medications may also play a role.

Keywords: Circadian rhythm; Critically ill patients; Delirium; Intensive care unit; Pain; Sedation.

Publication types

Review

MeSH terms

Analgesics / therapeutic use
Anesthesia
Chronobiology Disorders / therapy
Critical Illness*
Delirium / therapy
Humans
Hypnotics and Sedatives / therapeutic use*
Intensive Care Units
Respiration, Artificial
Sleep / physiology

Substances

Analgesics
Hypnotics and Sedatives