Antiphospholipid Antibody Syndrome: Raised Intracranial Pressure Without Cerebral Venous Sinus Thrombosis

Danielle S Rudich; Samuel H Yun; Anne Liebling; Jonathan E Silbert; Gilbert W Moeckel; Robert L Lesser

doi:10.1097/WNO.0000000000000277

Antiphospholipid Antibody Syndrome: Raised Intracranial Pressure Without Cerebral Venous Sinus Thrombosis

J Neuroophthalmol. 2015 Dec;35(4):396-9. doi: 10.1097/WNO.0000000000000277.

Authors

Danielle S Rudich¹, Samuel H Yun, Anne Liebling, Jonathan E Silbert, Gilbert W Moeckel, Robert L Lesser

Affiliation

¹ The Eye Care Group (DSR, JES, RLL), New Haven, Connecticut; Departments of Ophthalmology & Visual Sciences (DSR, SY, JES, RLL), Pathology and Nephrology (GWM), and Neurology (RLL), Yale University, New Haven, Connecticut; New Haven Rheumatology (AL), New Haven, Connecticut.

PMID: 26049680
DOI: 10.1097/WNO.0000000000000277

Abstract

Antiphospholipid antibody syndrome (APS) has been reported to cause elevated intracranial pressure, but usually this is due to cerebral venous sinus thrombosis (CVST). We present a 36-year old man with APS with elevated intracranial pressure with neuro-ophthalmic, renal and hematological involvement without identifiable CVST.

Publication types

Case Reports

MeSH terms

Adult
Antiphospholipid Syndrome / complications*
Humans
Intracranial Hypertension / etiology*
Kidney / pathology
Magnetic Resonance Angiography
Magnetic Resonance Imaging
Male
Papilledema / etiology
Sinus Thrombosis, Intracranial / physiopathology*
Visual Field Tests