Loss of HtrA1-induced attenuation of TGF-β signaling in fibroblasts might not be the main mechanism of CARASIL pathogenesis

Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):E1693. doi: 10.1073/pnas.1500911112. Epub 2015 Mar 13.

Authors

Ju Liu¹, Fengyun Dong², Josephine Hoh³

Affiliations

¹ Medical Research Center, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, Shandong 250014, China; and Department of Epidemiology and Public Health, Yale University, New Haven, CT 06520 ju.liu@sdu.edu.cn.
² Medical Research Center, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, Shandong 250014, China; and.
³ Department of Epidemiology and Public Health, Yale University, New Haven, CT 06520.

No abstract available

Publication types

Letter
Comment

MeSH terms

Alopecia / genetics*
Animals
Cerebral Infarction / genetics*
Humans
Latent TGF-beta Binding Proteins / physiology*
Leukoencephalopathies / genetics*
Serine Endopeptidases / physiology*
Spinal Diseases / genetics*
Transforming Growth Factor beta1 / physiology*

Substances

Latent TGF-beta Binding Proteins
Transforming Growth Factor beta1
Serine Endopeptidases