Hospital readmission and 30-day mortality after surgery for oral cavity cancer: Analysis of 21,681 cases

Head Neck. 2016 Apr:38 Suppl 1:E221-6. doi: 10.1002/hed.23973. Epub 2015 Sep 9.

Abstract

Background: Oral cavity squamous cell cancer (SCC) is treated primarily with surgery. Rates of 30-day hospital readmission and mortality after surgery for oral cavity SCC are unknown.

Methods: We conducted a retrospective analysis of postoperative 30-day unplanned readmission and mortality in patients with oral cavity SCC in the National Cancer Data Base (NCDB).

Results: Among 21,681 cases, the 30-day unplanned readmission rate was 3.2%, and the 30-day mortality rate was 1.0%. Male sex (odds ratio [OR] = 1.23; p = .02), stage T3 (OR = 1.55; p = .007), or T4 (OR = 1.52; p = .002), and neck dissection (OR = 1.37; p = .04) were independently associated with readmission. Age 76 to 85 years (OR = 4.80; p < .001), age >85 years (OR = 10.24; p < .001), comorbidity index ≥1 (OR = 2.31; p < .001), and stage T3 (OR = 3.02; p < .001) or T4 (OR = 3.24; p < .001) were associated with 30-day mortality.

Conclusion: Interventions aimed at decreasing hospital readmissions should target high-risk patients identified here. Factors associated with 30-day mortality reflect risk factors for overall mortality. © 2015 Wiley Periodicals, Inc. Head Neck 38: E221-E226, 2016.

Keywords: 30-day mortality; National Cancer Data Base (NCDB); head and neck cancer; oral cancer; readmission.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Female
  • Humans
  • Male
  • Middle Aged
  • Mouth Neoplasms / mortality*
  • Mouth Neoplasms / surgery*
  • Neoplasms, Squamous Cell / mortality
  • Neoplasms, Squamous Cell / surgery
  • Odds Ratio
  • Patient Readmission / statistics & numerical data*
  • Postoperative Complications
  • Retrospective Studies
  • Risk Factors