Oxaliplatin-related acute disseminated intravascular coagulation syndrome in a patient with metastatic colon cancer

Karen Malkhasyan; Stephanie Halene; Jill Lacy

doi:10.1016/j.clcc.2014.09.011

Oxaliplatin-related acute disseminated intravascular coagulation syndrome in a patient with metastatic colon cancer

Clin Colorectal Cancer. 2015 Mar;14(1):e9-e12. doi: 10.1016/j.clcc.2014.09.011. Epub 2014 Oct 2.

Authors

Karen Malkhasyan¹, Stephanie Halene², Jill Lacy²

Affiliations

¹ Yale-New Haven Hospital, Yale School of Medicine, New Haven, CT. Electronic address: karen.malkhasyan@yale.edu.
² Yale-New Haven Hospital, Yale School of Medicine, New Haven, CT.

PMID: 25446051
DOI: 10.1016/j.clcc.2014.09.011

No abstract available

Keywords: Acute hemolytic anemia; Colon cancer; Disseminated intravascular coagulation; FOLFOX6; Immune-mediated hematologic reaction; Oxaliplatin; Oxaliplatin-dependent antibodies.

Publication types

Case Reports

MeSH terms

Antineoplastic Combined Chemotherapy Protocols / adverse effects
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Colonic Neoplasms / drug therapy*
Colonic Neoplasms / pathology
Disseminated Intravascular Coagulation / chemically induced*
Fluorouracil / adverse effects
Fluorouracil / therapeutic use
Humans
Leucovorin / adverse effects
Leucovorin / therapeutic use
Male
Middle Aged
Neoplasm Metastasis
Organoplatinum Compounds / administration & dosage
Organoplatinum Compounds / adverse effects*
Organoplatinum Compounds / therapeutic use
Oxaliplatin

Substances

Organoplatinum Compounds
Oxaliplatin
Leucovorin
Fluorouracil

Supplementary concepts

Folfox protocol