Recent Insights into the Neurobiology of Impulsivity

Curr Addict Rep. 2014 Dec 1;1(4):309-319. doi: 10.1007/s40429-014-0037-4.

Abstract

Impulsivity is associated with various psychopathologies, and elevated impulsivity is typically disadvantageous. This manuscript reviews recent investigations into the neurobiology of impulsivity using human imaging techniques and animal models. Both human imaging and preclinical pharmacological manipulations have yielded important insights into the neurobiological underpinnings of impulsivity. A more thorough understanding of the complex neurobiology underlying aspects of impulsivity may provide insight into new treatment options that target elevated impulsivity and psychopathologies such as addictions.

Keywords: delay discounting; human; impulsivity; neuroimaging; rodent; translational.