Seizures and brain regulatory systems: consciousness, sleep, and autonomic systems

Madineh Sedigh-Sarvestani; Hal Blumenfeld; Tobias Loddenkemper; Lisa M Bateman

doi:10.1097/WNP.0000000000000133

Seizures and brain regulatory systems: consciousness, sleep, and autonomic systems

J Clin Neurophysiol. 2015 Jun;32(3):188-93. doi: 10.1097/WNP.0000000000000133.

Authors

Madineh Sedigh-Sarvestani¹, Hal Blumenfeld, Tobias Loddenkemper, Lisa M Bateman

Affiliation

¹ *Department of Neuroscience, University of Pennsylvania, Philadelphia, Pennsylvania, U.S.A.; †Departments of Neurology, Neurobiology and Neurosurgery, Yale School of Medicine, New Haven, Connecticut, U.S.A.; ‡Division of Epilepsy and Clinical Neurophysiology, Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, U.S.A.; and §Department of Neurology, Columbia University, New York, New York, U.S.A.

Abstract

Research into the physiologic underpinnings of epilepsy has revealed reciprocal relationships between seizures and the activity of several regulatory systems in the brain. This review highlights recent progress in understanding and using the relationships between seizures and the arousal or consciousness system, the sleep-wake and associated circadian system, and the central autonomic network.

Publication types

Review

MeSH terms

Animals
Brain / physiology*
Circadian Clocks
Consciousness / physiology*
Humans
Seizures / physiopathology*
Seizures / therapy
Sleep / physiology*

Abstract

Publication types

MeSH terms

Grants and funding