Capping a pulpotomy with calcium aluminosilicate cement: comparison to mineral trioxide aggregates

J Endod. 2014 Sep;40(9):1429-34. doi: 10.1016/j.joen.2014.02.001. Epub 2014 Apr 8.

Abstract

Introduction: Calcium aluminate cements have shown little affinity for bacterial growth, low toxicity, and immunogenicity when used as a restoration material, but calcium aluminate cements have not been tested in vivo in pulpotomy procedures.

Methods: To address this question, a calcium aluminosilicate cement (Quick-Set) was tested along with 2 mineral trioxide aggregates, ProRoot MTA and MTA Plus. These cements were used as a capping agent after pulpotomy. Control rats had no pulpotomy, or the pulpotomy was not capped. Proinflammatory cytokines interleukin (IL)-1β and IL-1α were measured, and histology was performed at 30 and 60 days after capping. The nociceptive response was determined by measuring the lengthening of the rat's meal duration.

Results: and

Conclusions: IL-1β and IL-1α concentrations were reduced in the capped teeth, but no differences were observed among the 3 cements. Dentinal bridging could be detected at both 30 and 60 days with each of the 3 cements, and the pulps were still vital 60 days after capping. Meal duration significantly shortened after placement of the 3 different cements, indicating a nociceptive response, but there were no differences among the materials. Calcium aluminosilicate cement had similar properties to mineral trioxide aggregates and is a viable option for pulpotomy procedures.

Keywords: Calcium aluminate/aluminosilicate cement; calcium silicate; endodontic; mineral trioxide aggregate; pain; tricalcium silicate.

Publication types

  • Comparative Study
  • Research Support, N.I.H., Extramural

MeSH terms

  • Aluminum Compounds / therapeutic use*
  • Aluminum Silicates / therapeutic use*
  • Animals
  • Bacterial Load
  • Calcium Compounds / therapeutic use*
  • Clay
  • Dental Cements / therapeutic use*
  • Dental Pulp / cytology
  • Dental Pulp / microbiology
  • Dental Pulp / physiology
  • Dentin, Secondary / drug effects
  • Drug Combinations
  • Eating / physiology
  • Inflammation Mediators / analysis
  • Interleukin-1alpha / analysis
  • Interleukin-1beta / analysis
  • Materials Testing
  • Nociception / drug effects
  • Oxides / therapeutic use*
  • Pulp Capping and Pulpectomy Agents / therapeutic use*
  • Pulpotomy / methods
  • Rats
  • Silicates / therapeutic use*
  • Time Factors
  • Tissue Survival / drug effects

Substances

  • Aluminum Compounds
  • Aluminum Silicates
  • Calcium Compounds
  • Dental Cements
  • Drug Combinations
  • Inflammation Mediators
  • Interleukin-1alpha
  • Interleukin-1beta
  • Oxides
  • Pulp Capping and Pulpectomy Agents
  • Quick-Set
  • Silicates
  • mineral trioxide aggregate
  • Clay