Abstract
Pathogenic bacteria secrete effector proteins that target host cell Rho GTPases to manipulate the actin cytoskeleton. A recent study in Nature identifies the Pyrin inflammasome as a sensor of this pathogenic process.
Publication types
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Research Support, Non-U.S. Gov't
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Comment
MeSH terms
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Animals
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Cytoskeletal Proteins / metabolism*
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Humans
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Immunity, Innate / immunology*
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Inflammasomes / metabolism*
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rho GTP-Binding Proteins / metabolism*
Substances
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Cytoskeletal Proteins
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Inflammasomes
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rho GTP-Binding Proteins