Objective: A foreign body giant cell (FBGC) reaction may occur in response to implanted xenogenic biomaterials. Here we report a FBGC reaction to the recently introduced xenogenic biomaterial, tarSys™, used for correction of lower eyelid retraction.
Method: A retrospective chart review of two patients with FBGC reaction to tarSys™ implantation was performed.
Results: Two patients (aged 51, 58 year) with lower eyelid retraction underwent surgical implantation of tarSys™ spacer grafts for correction. Both patients subsequently experienced chronic swelling requiring graft removal. Examination of the specimens showed a palisading FBGC reaction around acellular pink fibrillar material.
Conclusion: A FBGC reaction may follow implantation of the tarSys™ xenograft.
Keywords: allograft; eyelid; foreign body giant cell reaction; rejection; xenograft.
© 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.