Cryptococcal meningitis immune reconstitution inflammatory syndrome (IRIS) is frequently seen in patients with HIV and less frequently in patients on immune suppressive medications for other conditions. Here, we describe the first reported case of unmasking cryptococcal IRIS due to granulocyte colony-stimulating factor used in an HIV-negative patient with chemotherapy-induced neutropenia.
Keywords: Chemotherapy; Cryptococcal meningitis; Granulocyte colony-stimulating factor; Immune reconstitution inflammatory syndrome; Immunosuppressed host.