Long noncoding RNAs in erythropoiesis

Blood. 2014 Jan 23;123(4):465-6. doi: 10.1182/blood-2013-12-538306.

Abstract

In this issue of Blood, Alvarez-Dominguez et al use a combination of genomics technology, bioinformatics, and functional analyses to provide new insights into our understanding of the role of long noncoding RNAs (lncRNAs) in erythropoiesis.1 This is an initial step forward in our understanding of the many roles of lncRNAs in normal and perturbed erythropoiesis. lncRNAs have recently emerged as critical, multifunctional regulators of cellular gene expression.

Publication types

  • Comment

MeSH terms

  • Animals
  • Basic Helix-Loop-Helix Transcription Factors / metabolism*
  • Erythrocytes / cytology*
  • GATA1 Transcription Factor / metabolism*
  • Humans
  • Kruppel-Like Transcription Factors / metabolism*
  • Proto-Oncogene Proteins / metabolism*
  • RNA, Long Noncoding*
  • T-Cell Acute Lymphocytic Leukemia Protein 1

Substances

  • Basic Helix-Loop-Helix Transcription Factors
  • GATA1 Transcription Factor
  • Gata1 protein, mouse
  • Kruppel-Like Transcription Factors
  • Proto-Oncogene Proteins
  • RNA, Long Noncoding
  • T-Cell Acute Lymphocytic Leukemia Protein 1
  • Tal1 protein, mouse
  • erythroid Kruppel-like factor