Selection of neighborhood controls for a population-based Lyme disease case-control study by using a commercial marketing database

Am J Epidemiol. 2013 Jul 15;178(2):276-9. doi: 10.1093/aje/kws464. Epub 2013 May 21.

Abstract

The selection of controls is an important methodological consideration for case-control studies. Neighborhood-matched control selection is particularly crucial for studies of vector-borne disease, such as Lyme disease, for which risk is intrinsically linked to geographical location. The matching of case-control pairs on neighborhood can help control for variation in ecological risk factors that are tied to geographical location, like vector and host habitat in the peridomestic environment. Random-digit dialing has been used to find neighborhood controls by using the area code and exchange of the case to generate lists of potential control households. An alternative to random-digit dialing is the purchase of residential telephone numbers from a commercial marketing database. This report describes the utility of the InfoUSA.com (InfoGroup, Papillion, Nebraska) commercial marketing database for neighborhood control recruitment in a Lyme disease case-control study in Connecticut during 2005-2007.

Keywords: Lyme disease; case-control studies; data collection; geographic information systems; methodological study; telephone.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Case-Control Studies*
  • Connecticut
  • Data Collection / methods*
  • Databases, Factual*
  • Geographic Information Systems
  • Humans
  • Lyme Disease / etiology*
  • Matched-Pair Analysis*
  • Patient Selection*
  • Risk Factors