Different routes to the same destination

Elife. 2013 Feb 19:2:e00572. doi: 10.7554/eLife.00572.

Abstract

The toll-like receptors that detect viral DNA and viral RNA in cells take different paths from the endoplasmic reticulum to the endosome.

Keywords: AP-2; Mouse; Toll-like receptors; UNC93B1; trafficking.

MeSH terms

  • Animals
  • Biological Transport
  • DNA, Viral / metabolism*
  • Endoplasmic Reticulum / metabolism*
  • Endosomes / metabolism*
  • Mice
  • RNA, Viral / metabolism*
  • Toll-Like Receptors / metabolism
  • Toll-Like Receptors / physiology*

Substances

  • DNA, Viral
  • RNA, Viral
  • Toll-Like Receptors