Metastatic gastrinoma in a pediatric patient with Zollinger-Ellison syndrome

Stephanie A Massaro; Sukru H Emre

doi:10.1097/MPH.0b013e318282dadf

Metastatic gastrinoma in a pediatric patient with Zollinger-Ellison syndrome

J Pediatr Hematol Oncol. 2014 Jan;36(1):e13-5. doi: 10.1097/MPH.0b013e318282dadf.

Authors

Stephanie A Massaro¹, Sukru H Emre

Affiliation

¹ *Section of Hematology/Oncology, Department of Pediatrics †Yale Stem Cell Center, Yale University School of Medicine ‡Section of Transplantation and Immunology, Department of Surgery §Yale New Haven Transplant Center, New Haven, CT.

PMID: 23426004
DOI: 10.1097/MPH.0b013e318282dadf

Abstract

Metastatic neuroendocrine tumors of childhood are extremely rare, and as such present diagnostic and therapeutic challenges. Here, we report a case of gastrinoma with extensive hepatic metastases in a pediatric patient with Zollinger-Ellison Syndrome who underwent orthotopic liver transplant followed by cytotoxic chemotherapy, somatostatin analog therapy, and immune modulation.

Publication types

Case Reports

MeSH terms

Child
Combined Modality Therapy
Female
Gastrinoma / complications
Gastrinoma / secondary*
Gastrinoma / surgery
Humans
Liver Neoplasms / complications
Liver Neoplasms / secondary*
Liver Neoplasms / surgery
Liver Transplantation
Pancreatic Neoplasms / complications
Pancreatic Neoplasms / pathology*
Pancreatic Neoplasms / surgery
Zollinger-Ellison Syndrome / complications*