Acute portal vein thrombosis complicating in vitro fertilization

Fertil Steril. 2012 Dec;98(6):1470-3. doi: 10.1016/j.fertnstert.2012.08.010. Epub 2012 Sep 8.

Abstract

Objective: To describe a case of acute portal vein thrombosis after IVF treatment.

Design: Case report.

Setting: University teaching hospital.

Patient(s): A 39-year-old woman experienced worsening, right upper quadrant pain several days after oocyte retrieval; ET was withheld. Imaging studies revealed acute portal vein thrombosis with extension into the splenic and superior mesenteric veins.

Intervention(s): Therapeutic anticoagulation; no ET was performed.

Main outcome measure(s): Improvement in symptoms, accurate diagnosis of condition.

Result(s): Decreased size of portal vein thrombosis and partial vessel recanalization.

Conclusion(s): Thromboembolic events are a rare complication of assisted reproductive technology (ART). In women who present with upper abdominal pain during ART, portal vein thrombosis should be considered in the differential diagnosis.

Publication types

  • Case Reports

MeSH terms

  • Abdominal Pain / diagnosis*
  • Abdominal Pain / etiology*
  • Abdominal Pain / prevention & control
  • Adult
  • Female
  • Fertilization in Vitro / adverse effects*
  • Fibrinolytic Agents / therapeutic use
  • Humans
  • Portal Vein / diagnostic imaging*
  • Radiography
  • Treatment Outcome
  • Venous Thrombosis / diagnosis*
  • Venous Thrombosis / drug therapy
  • Venous Thrombosis / etiology*

Substances

  • Fibrinolytic Agents