Abstract
A recent study in the journal Science offers insights into the mechanism behind feto-maternal tolerance, as evidenced by changes in the immuno-logical environment of the uterus and decidua. They also provide a rich area of research for the understanding of the regulation of the immune system in other complicated medical conditions, including cancer and pregnancies affected by infection or autoimmunity.
© 2012 John Wiley & Sons A/S.
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Animals
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Cell Communication
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Cell Movement / drug effects
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Cellular Microenvironment
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Chemokine CXCL10 / metabolism
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Chemokine CXCL9 / metabolism
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Female
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Humans
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Immune Tolerance
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Immunomodulation
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Maternal-Fetal Exchange / immunology*
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Phenanthridines / immunology*
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Pregnancy
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Stromal Cells / immunology*
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T-Lymphocytes / immunology*
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Th1-Th2 Balance
Substances
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Chemokine CXCL10
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Chemokine CXCL9
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Phenanthridines
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decidium