Losing the lust for life: a new role for an old feeding Peptide?

Neuron. 2012 Aug 9;75(3):360-2. doi: 10.1016/j.neuron.2012.07.018.

Abstract

A recent paper in Nature (Lim et al., 2012) describes the effects of melanocortin receptors in the nucleus accumbens. The studies connect a hypothalamic peptide system with brain reward centers and show effects on specific neuronal populations and behavioral components of mood.

Publication types

  • Comment

MeSH terms

  • Anhedonia / physiology*
  • Animals
  • Electrical Synapses / metabolism*
  • Nucleus Accumbens / pathology*
  • Receptor, Melanocortin, Type 4 / metabolism*
  • Signal Transduction*
  • Stress, Psychological / pathology*

Substances

  • Receptor, Melanocortin, Type 4