Germs gone wild

Nat Med. 2012 May 4;18(5):654-6. doi: 10.1038/nm.2767.

Abstract

The normally harmless behavior of bacteria in the intestinal tract is maintained by community structure and the integrity of host defenses. When either or both of these are compromised, a few disgruntled outcasts can cause a riot, taking down the whole neighborhood (pages 799-806).

Publication types

  • Comment

MeSH terms

  • Animals
  • Anti-Bacterial Agents / pharmacology*
  • Apoptosis Regulatory Proteins / physiology*
  • Calcium-Binding Proteins / physiology*
  • Escherichia coli / drug effects*
  • Inflammasomes / physiology*
  • Intestines / microbiology*
  • Metagenome / drug effects*
  • Neuronal Apoptosis-Inhibitory Protein / physiology*

Substances

  • Anti-Bacterial Agents
  • Apoptosis Regulatory Proteins
  • Calcium-Binding Proteins
  • Inflammasomes
  • Ipaf protein, mouse
  • Naip5 protein, mouse
  • Neuronal Apoptosis-Inhibitory Protein