Reversible leukoencephalopathy with stroke-like presentation in a patient with 5-dihydropyrimidine dehydrogenase deficiency treated with continuous 5-fluorouracil infusion

Clin Colorectal Cancer. 2012 Sep;11(3):215-7. doi: 10.1016/j.clcc.2012.01.004. Epub 2012 Mar 10.

Authors

Jia Li¹, James J Lee, Edward Chu, Joachim M Baehring

Affiliation

¹ Section of Medical Oncology, Department of Internal Medicine, Connecticut VA Healthcare System, Yale, Comprehensive Cancer Center, Yale University School of Medicine, New Haven, CT 06510, USA.

PMID: 22410472
DOI: 10.1016/j.clcc.2012.01.004

No abstract available

Publication types

Case Reports

MeSH terms

Antineoplastic Combined Chemotherapy Protocols / administration & dosage
Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
Chemotherapy, Adjuvant
Colonic Neoplasms / complications
Colonic Neoplasms / drug therapy*
Colonic Neoplasms / surgery
Dihydropyrimidine Dehydrogenase Deficiency / complications*
Female
Fluorouracil / administration & dosage
Fluorouracil / adverse effects*
Humans
Leucovorin / administration & dosage
Leukoencephalopathies / chemically induced*
Leukoencephalopathies / diagnosis
Lymphatic Metastasis
Middle Aged
Organoplatinum Compounds / administration & dosage

Substances

Organoplatinum Compounds
Leucovorin
Fluorouracil

Supplementary concepts

Folfox protocol