Modeling cellular signaling: taking space into the computation

Nat Methods. 2012 Feb 28;9(3):239-42. doi: 10.1038/nmeth.1900.

Abstract

In living systems, chemical reactions and the geometry of cells feed back on each other. Methods for computational modeling are beginning to take this complexity into account.

MeSH terms

  • Animals
  • Cell Size*
  • Computer Simulation
  • Humans
  • Models, Anatomic*
  • Models, Biological*
  • Signal Transduction / physiology*