Single chain variable fragment CD7 antibody conjugated PLGA/HDAC inhibitor immuno-nanoparticles: developing human T cell-specific nano-technology for delivery of therapeutic drugs targeting latent HIV

J Control Release. 2011 Nov 30:152 Suppl 1:e9-10. doi: 10.1016/j.jconrel.2011.08.089.
No abstract available

MeSH terms

  • Anti-HIV Agents / chemistry
  • Anti-HIV Agents / metabolism
  • Anti-HIV Agents / pharmacology*
  • Anti-HIV Agents / toxicity
  • Antigens, CD7 / immunology*
  • Cell Line
  • Chemistry, Pharmaceutical
  • Chromatography, High Pressure Liquid
  • Delayed-Action Preparations
  • Drug Carriers*
  • Drug Compounding
  • Flow Cytometry
  • HIV / drug effects*
  • HIV / physiology
  • Histone Deacetylase Inhibitors / chemistry
  • Histone Deacetylase Inhibitors / metabolism
  • Histone Deacetylase Inhibitors / pharmacology*
  • Histone Deacetylase Inhibitors / toxicity
  • Humans
  • Immunoconjugates / chemistry
  • Immunoconjugates / metabolism
  • Immunoconjugates / pharmacology*
  • Immunoconjugates / toxicity
  • Lactic Acid / chemistry*
  • Microscopy, Electron, Scanning
  • Nanoparticles*
  • Nanotechnology
  • Particle Size
  • Polyglycolic Acid / chemistry*
  • Polylactic Acid-Polyglycolic Acid Copolymer
  • Single-Chain Antibodies / chemistry
  • Single-Chain Antibodies / metabolism*
  • T-Lymphocytes / immunology
  • T-Lymphocytes / metabolism*
  • T-Lymphocytes / virology
  • Technology, Pharmaceutical / methods
  • Virus Latency

Substances

  • Anti-HIV Agents
  • Antigens, CD7
  • Delayed-Action Preparations
  • Drug Carriers
  • Histone Deacetylase Inhibitors
  • Immunoconjugates
  • Single-Chain Antibodies
  • Polylactic Acid-Polyglycolic Acid Copolymer
  • Polyglycolic Acid
  • Lactic Acid