Relapse of polymicrobial endocarditis in an intravenous drug user

Yale J Biol Med. 2011 Sep;84(3):321-4.

Abstract

A 26-year-old male intravenous drug user (IDU) presented twice within 6 months with relapsed polymicrobial infective endocarditis (IE) due to Eikenella corrodens and Streptococcus constellatus after completing two courses of appropriate antimicrobial therapy. This report points to relapsing endocarditis as a clinical entity that warrants attention in IDUs when E. corrodens or S. constellatus are causative agents of IE.

Keywords: endocarditis; polymicrobial; relapse.

Publication types

  • Case Reports
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Ceftriaxone / pharmacology
  • Coinfection / microbiology*
  • Eikenella corrodens / isolation & purification
  • Eikenella corrodens / pathogenicity*
  • Endocarditis, Bacterial / microbiology*
  • Gram-Negative Bacterial Infections / drug therapy*
  • Gram-Negative Bacterial Infections / microbiology
  • Humans
  • Male
  • Metronidazole / pharmacology
  • Oxacillin / pharmacology
  • Recurrence
  • Streptococcal Infections / drug therapy*
  • Streptococcal Infections / microbiology
  • Streptococcus constellatus / isolation & purification
  • Streptococcus constellatus / pathogenicity*
  • Substance-Related Disorders

Substances

  • Metronidazole
  • Ceftriaxone
  • Oxacillin