Malaria: an evaluation of the current state of research on pathogenesis and antimalarial drugs

Yale J Biol Med. 2010 Dec;83(4):185-91.

Abstract

This brief review provides an overview of the pathogenesis of malaria, the human immune response to malaria, current methodology for malaria diagnosis, and current antimalarial drug regimens. The review also provides a critical evaluation of the research directions in the areas of drug design and vaccine design.

Keywords: antimalarial drugs; immune response; malaria; mosquito; vaccines.

Publication types

  • Review

MeSH terms

  • Antimalarials / therapeutic use*
  • Drug Design
  • Humans
  • Malaria / diagnosis*
  • Malaria / drug therapy*
  • Malaria / immunology
  • Malaria / transmission
  • Malaria Vaccines / therapeutic use

Substances

  • Antimalarials
  • Malaria Vaccines