Checks and balances: IL-23 in the intestine

Immunity. 2010 Aug 27;33(2):150-2. doi: 10.1016/j.immuni.2010.08.005.

Abstract

In this issue of Immunity, Ahern et al. (2010) show that IL-23R signaling in CD4(+) T cells induces effector and suppresses regulatory CD4(+) T cells, which is critical for the development of intestinal, but not systemic, inflammation.

Publication types

  • Comment
  • Research Support, Non-U.S. Gov't