Muir-Torre syndrome: Facts and controversies

Clin Dermatol. 2010 May-Jun;28(3):324-9. doi: 10.1016/j.clindermatol.2009.07.001.

Abstract

The cutaneous presentation of a tumor sometimes has implications for a patient and his or her family, and Muir-Torre syndrome is an example of this. Because a single skin lesion can have broad consequences, it is important for clinicians to be aware of Muir-Torre syndrome. The definition, potential clues, the role of ancillary testing (microsatellite, immunohistochemical, and genetic), and screening recommendations are reviewed.

MeSH terms

  • Early Detection of Cancer / methods
  • Genetic Testing
  • Humans
  • Immunohistochemistry
  • Microsatellite Instability
  • Muir-Torre Syndrome / diagnosis*
  • Muir-Torre Syndrome / genetics
  • Practice Guidelines as Topic
  • Risk Factors