Medication effects on sleep

Francoise J Roux; Meir H Kryger

doi:10.1016/j.ccm.2010.02.008

Medication effects on sleep

Clin Chest Med. 2010 Jun;31(2):397-405. doi: 10.1016/j.ccm.2010.02.008.

Authors

Francoise J Roux¹, Meir H Kryger

Affiliation

¹ Section of Pulmonary and Critical Care Medicine, Yale University School of Medicine, 333 Cedar Street, Post Office Box 208057, New Haven, CT 06520-8057, USA. francoise.roux@yale.edu

PMID: 20488296
DOI: 10.1016/j.ccm.2010.02.008

Abstract

The understanding of the neuropharmacologic reciprocal interactions between the sleep and wake cycles has progressed significantly in the past decade. It was also recently appreciated that sleep disruption or deprivation can have adverse metabolic consequences. Multiple medications have a direct or indirect impact on sleep and the waking state. This article reviews how commonly prescribed medications can significantly affect the sleep-wake cycle.

Publication types

Review

MeSH terms

Antiparkinson Agents / pharmacology
Antipsychotic Agents / pharmacology
Benzhydryl Compounds / pharmacology
Benzodiazepines / pharmacology
Histamine Antagonists / pharmacology
Humans
Lithium / pharmacology
Modafinil
Selective Serotonin Reuptake Inhibitors / pharmacology
Sleep / drug effects*
Theophylline / pharmacology
Wakefulness / physiology

Substances

Antiparkinson Agents
Antipsychotic Agents
Benzhydryl Compounds
Histamine Antagonists
Serotonin Uptake Inhibitors
Benzodiazepines
Lithium
Theophylline
Modafinil