Linear free-energy relationship analysis of a catalytic desymmetrization reaction of a diarylmethane-bis(phenol)

Org Lett. 2010 Jun 18;12(12):2794-7. doi: 10.1021/ol100927m.

Abstract

Linear free-energy relationships have been found for enantioselectivity and various steric parameters in an enantioselective desymmetrization of symmetrical bis(phenol) substrates. The potential origin of this observation and the role of different steric parameters are discussed.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Catalysis
  • Linear Energy Transfer
  • Molecular Structure
  • Phenol / chemistry*
  • Stereoisomerism

Substances

  • Phenol