Genetic testing in aortic aneurysm disease: CON

Cardiol Clin. 2010 May;28(2):199-204. doi: 10.1016/j.ccl.2010.02.002.

Abstract

Surgery on the thoracic aorta is challenging, dangerous, intricate, complex, demanding, and tremendously rewarding. Yet, we need to raise our understanding of aortic disease to a higher plane. Linkage analysis and genetic sequencing techniques have been used to understand thoracic aortic aneurysm and dissection. Although these genetic breakthroughs are exciting and important, this article espouses the CON point of view that routine genetic testing is not practical or clinically essential at the present time.

Publication types

  • Comment
  • Review

MeSH terms

  • Aortic Aneurysm / diagnosis*
  • Aortic Aneurysm / genetics
  • Chromosome Mapping / methods
  • DNA / analysis*
  • Genetic Predisposition to Disease
  • Genetic Testing / methods*
  • Humans

Substances

  • DNA