Extensively drug-resistant tuberculosis: a new face to an old pathogen

Annu Rev Med. 2009:60:307-20. doi: 10.1146/annurev.med.60.053107.103955.

Abstract

The presence and consequences of resistance to drugs used for the treatment of tuberculosis have long been neglected. The recent detection and recognition of widespread multiple-drug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis have raised interest and concern among clinicians and public health authorities globally. In this article, we describe the current global status of drug-resistant tuberculosis. We discuss the development of resistance, current management, and strategies for control.

Publication types

  • Review

MeSH terms

  • Extensively Drug-Resistant Tuberculosis* / complications
  • Extensively Drug-Resistant Tuberculosis* / diagnosis
  • Extensively Drug-Resistant Tuberculosis* / drug therapy
  • Extensively Drug-Resistant Tuberculosis* / etiology
  • Humans
  • Risk Factors