This article discusses the basic principles of dynamic contrast-enhanced MR imaging (DCE-MR imaging) of the breast, including technical parameters, image acquisition, and image interpretation. Clinical DCE-MR imaging of the breast has undergone considerable growth from a once investigational technique to an important clinical tool in widespread use. Progress in MR technology and refinement of MR imaging parameters now allow for concurrent acquisition of high-spatial-resolution and adequate-temporal-resolution images, which are necessary for accurate assessment of breast lesion morphology and qualitative kinetic analysis. More advanced DCE-MR imaging techniques involving higher-temporal-resolution images and rigorous quantitative analysis of the time signal enhancement curves are currently an area of research.