Local advantage: skin DCs prime; skin memory T cells protect

Nat Immunol. 2009 May;10(5):451-3. doi: 10.1038/ni0509-451.

Abstract

How the immune system responds to local infection and establish protective immunity within the susceptible tissue remains unclear. Two new studies show local tissue-resident DCs prime CTL responses and memory CTLs remain within the tissue to provide antiviral immunity.

Publication types

  • Comment
  • News

MeSH terms

  • Dendritic Cells / immunology*
  • Humans
  • Immunologic Memory*
  • Lymphocyte Activation / immunology*
  • Skin / immunology*
  • Skin Diseases, Infectious / immunology*
  • T-Lymphocytes, Cytotoxic / immunology*