Critical care outcomes in the hematologic transplant recipient

John R McArdle

doi:10.1016/j.ccm.2008.10.002

Critical care outcomes in the hematologic transplant recipient

Clin Chest Med. 2009 Mar;30(1):155-67, ix-x. doi: 10.1016/j.ccm.2008.10.002.

Author

John R McArdle¹

Affiliation

¹ Department of Medicine, Yale University School of Medicine, New Haven, CT 06073, USA. john.mcardle@yale.edu

PMID: 19186287
DOI: 10.1016/j.ccm.2008.10.002

Abstract

Critical illness is a dreaded complication in recipients of hematologic stem cell transplantation, with poor survival described in a number of early series. The perception of futility may impact the approach to therapy. Over the last 20 years, there have been significant advances in the application of intensive care, as well as changes in the management of patients before, during, and after transplantation. These advances and changes may have an impact on this traditionally poor survival. This article discusses the outcomes of critical illness in bone marrow and stem cell transplant recipients, and gives possible reasons for the apparent improvement in outcomes seen in more recent series.

Publication types

Review

MeSH terms

Bone Marrow Transplantation / adverse effects*
Bone Marrow Transplantation / mortality
Critical Care / methods*
Critical Illness / mortality
Critical Illness / therapy*
Humans
Intensive Care Units
Postoperative Complications / mortality
Postoperative Complications / prevention & control*
Stem Cell Transplantation / adverse effects*
Stem Cell Transplantation / mortality