Sensor-augmented pump therapy in type 1 diabetes

Curr Opin Endocrinol Diabetes Obes. 2008 Apr;15(2):118-22. doi: 10.1097/MED.0b013e3282f7960b.

Abstract

Purpose of review: Recent developments in technology have ushered in a new era of managing type 1 diabetes. Continuous glucose monitoring is rapidly becoming an accepted adjunct to traditional self-monitoring of plasma glucose, and the marriage of continuous glucose sensors to continuous subcutaneous insulin infusion is the first step towards the development of a true artificial pancreas. The purpose of this review is to familiarize the reader with the new glucose sensors and discuss the literature evaluating their accuracy and effectiveness.

Recent findings: Current models of continuous glucose sensors are still less accurate than traditional methods of blood glucose monitoring but provide information regarding trends that cannot be obtained with blood testing. Short-term studies of continuous glucose sensors have demonstrated reduction in glycosylated hemoglobin levels and time spent in hypo- and hyperglycemic ranges. Patient acceptance and satisfaction with sensors has been shown to depend on the quality of the data, comfort of wear, and ease of use.

Summary: Sensor-augmented pump therapy represents a landmark improvement in diabetes treatment and will likely become the standard of care. Future work should focus on improvements in sensor accuracy and development of user-friendly algorithms to assist patients with self-management.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Biosensing Techniques
  • Blood Glucose / analysis*
  • Clinical Trials as Topic
  • Diabetes Mellitus, Type 1 / blood
  • Diabetes Mellitus, Type 1 / drug therapy*
  • Equipment Design
  • Humans
  • Insulin Infusion Systems*
  • Monitoring, Physiologic / methods

Substances

  • Blood Glucose